Yes, you should perform a clean installation after replacing the motherboard, CPU, and RAM.
Yes, you should perform a clean installation after replacing the motherboard, CPU, and RAM.
I've only tried this with the same brand of motherboard (MSI, ranging from B450 to an X570), making sure to update the BIOS and drivers. It worked well. While a clean install is ideal, sometimes finding software disks or downloading files takes too much effort. I recommend backing up your important data first, then give it a shot. If conflicts arise, you can revert and perform the clean install.
I'll proceed with that change. Switching from a Gigabyte to an Asus motherboard might not be the best move right now. I just didn't want to deal with reinstalling all my apps and having to recall my 50 forgotten passwords.