Yes, the AMD RX 480 should work with your Mai Z68s-G43 (G3).
Yes, the AMD RX 480 should work with your Mai Z68s-G43 (G3).
The system is still fresh enough to include UEFI in BIOS, which is why some RX 4xx cards fail on older setups due to missing UEFI support or extensions. Verify the power source can manage it—typically around 180-200 watts from a 12V output is required for the RX 480, ensuring the PSU delivers at least 350 watts on 12V.