Yes, a Pop!_OS 21.04 live installer can function with UEFI.
Yes, a Pop!_OS 21.04 live installer can function with UEFI.
This would only become important if your system reports an issue with mmx64.efi being absent. It's possible but not typical on my machine. You might need to follow the steps I mentioned before a USB boot in any mode other than legacy support works. With UEFI activated, the system would indicate that /efi/boot/mmx64.efi is missing. I obtained this file from an Ubuntu ISO USB drive formatted as FAT32 using a program like 7-zip, then copied it to the root directory on the drive. You can download the Ubuntu ISO and open it in 7-Zip, moving /efi/boot/mmx64.efi to /efi/boot. If successful, you should be able to boot from that USB drive. Updated August 19, 2021 by teknohpile clarification
My basic grasp of UEFI is still developing. At first, I turned off secureboot and removed the encryption keys. However, my old HP notebook kept showing errors about the missing /boot/efi/mmx64.efi file unless I used legacy support mode.