Reversed version of RDR2 layout
Reversed version of RDR2 layout
You're experiencing an issue with your upside-down monitor and the landscape flip not applying correctly in Windows. It seems the problem persists even when switching to landscape mode during playback. Check your display settings and ensure the correct resolution is selected. If the issue continues, consider updating your graphics drivers or consulting your monitor's support resources.
You might exchange the screens so the ultra-wide display sits at the base.
Did you attempt using ctrl-alt-<arrow key>? Are you viewing fullscreen mode? Have you used a window or windowed fullscreen option?