Yes, a virus can harm encrypted drives.
Yes, a virus can harm encrypted drives.
You have three drives, with two having default encryption and the third being unlocked. A virus originating from the unlocked drive could potentially spread to the other drives and cause damage to their files.
It really depends on the situation. When the drive is unlocked, it usually works just like any other drive—programs can read and write without problems. You also need the virus active; a virus executable isn’t necessary. Unless it’s already running (there are many ways to start it), you should remove the virus if you suspect one. It’s best to avoid risking your system. If you’re unsure, consider scanning the drive with an offline tool.