Use a designated hot key to turn off the second monitor.
Use a designated hot key to turn off the second monitor.
It might be adjustable, but achieving it will likely require significant work.
The simplest approach is to capture a macro and program it to respond to a particular key press. Then reverse the action to reverse it. AutoHotkey can handle this if you're proficient enough. With three monitors and NVIDIA Surround set up, you can switch between surround mode and single display using Ctrl+Alt+R
Could be done using AutoHotKey and triggering it via a shortcut... Egh.
Various screen settings are supported by DisplayFusion to achieve this functionality.